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SANTE/2020/12830: New Guidance for analytical method validation

The new “Guidance Document on Pesticide Analytical Methods for Risk Assessment and Post-approval Control and Monitoring Purposes”, came into force in February 2021 (SANTE/2020/12830, Rev.1). It supersedes Guidance Documents SANCO/3029/99 and SANCO/825/00. Main changes include:

  • Method validation needs to be performed in each lab involved in data generation
  • New calibration requirements
  • Detailed description for assessment of matrix effects, stability, and confirmatory methods
  • New definition of LOD and LOQ
  • New matrix groups have been defined
  • Hazardous reagents have been banned

LAUS is working according to the newest guidelines. Contact us for more information.


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