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Classification and Labeling of Substances and Mixtures according to CLP / GHS / ADR


The classification and labeling of chemicals makes handling safer with respect to human health and the environment. The Globally Harmonised System (GHS) is a uniform system for the classification of chemicals and mixtures and their labelling on packaging as well as in safety data sheets. With the GHS the United Nations provide an internationally agreed standard for classification and labelling with hazard statements (H-phrases) and pictograms. It applies worldwide for use during manufacture, transport and handling.

The CLP Regulation (Classification, Labelling and Packaging, Regulation (EC) No 1272/2008) incorporates the classification criteria and labelling rules of the GHS for the European Union. Since 2010 it requires companies to classify, label and package chemicals before placing them on the market. It was extended to mixtures in 2015.

The ADR is the European Agreement concerning the International Carriage of Dangerous Goods by Road. It comprises special aspects for transportation in accordance with GHS and CLP.

LAUS can support you with the determination of relevant endpoints for the classification of substances according to GHS, CLP and ADR with studies from the following areas:


Physical hazards:
Explosives (Screening)
Flammable liquids (H224, H225, H226)
Flammable solids (H228)
Pyrophoric liquids (H250)
Pyrophoric solids (H250)
Self-heating substances and mixtures (H251, H252)
Substances and mixtures which, in contact with water, emit flammable gases (H260, H261)
Oxidizing solids (H271, H272)
Corrosive to metals (H290)


Health hazards:
Skin corrosion/irritation (H314, H315)
Serious eye damage/eye irritation (H318, H319)


Environmental hazards:
Hazardous to the aquatic environment, short-term (acute) (H400, H401, H402)
Hazardous to the aquatic environment, long-term (chronic) (H410, H411, H412, H413)


We are looking forward to arrange an appointment with you to develop a customized test strategy for your substance.

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