The Fourier Transform Infrared Spectroscopy (FTIR) spectrum of a polymer is like a fingerprint and allows its identification.
The ATR (Attenuated total reflection) method enables us to analyse all kinds of polymers (solid, powder, films, granules, soluble, etc.) directly or after grinding. The FTIR spectrum collected in the wavenumber range 500cm-1-4000cm-1 will be compared with our polymer data base containing more than 10.000 spectra. The best matches are being reported.
Why can the determination of the Particle Size Distribution (PSD) be challenging?
The PSD is required for a number of regulatory purposes:
granulometry for the REACH dossier of solid substances (OECD 110)
REACH substance identity profile (sameness) for Nanomaterials
the definition of nanoforms
analytical determination of nano materials in genotoxicity or ecotoxicological studies
The smaller the particles are, the more elaborate the techniques have to be. LAUS has equipped a new lab with state-of-the-art technology and trained a highly qualified study director. We have developed a deeper understanding on how to approach the different substance types (e. g. nanomaterials) and how to receive comprehensive results. Sometimes complementary techniques like SEM/TEM, XRD with Rietveld or BET are required to describe a substance in its entity.
For Plastic Food Contact Materials EFSA requires genotoxicity testing including a minimum of two in vitro studies:
i) A bacterial reverse mutation test
ii) An in vitro mammalian cell micronucleus test
In a first step the specific migration limits (SML) expressed in mg of substance per kg of food (mg/kg) needs to be determined for the packaging material. If the exposure through migration is low, this limited data set might be sufficient. If the exposure is higher, a strategy with more toxicological information will be required.
If you want to get access to data sharing under chemical legislation around the world, you need a Substance Identity (also known as “Sameness”) of your substance.
- EU REACH
- China REACH
- Korea: AREC („Act on the Registration and Evaluation of Chemical Substances“), K-REACH
- Türkiye: KKDIK, Türkiye REACH
- United Kingdom: UK REACH
Our experts will gladly choose the required analyses for your substance. Ask us for a quotation.
A NRES is a new registrant of a substance that was previously registered under EU REACH before 1 January 2021 by any legal entity.
First step in the process is to submit an Article 26 inquiry according to UK REACH. When the NRES status has been confirmed, 2, 4 or 6 years plus 300 days from the end of the transition period (i.e. from 31 December 2020) remain for the submission of the full information requirements.
If you are a non-GB based manufacturer or formulator your OR must submit analytical data generated from a sample manufactured by you or your non-GB based manufacturer for an Article 26 inquiry under UK REACH:
An inquiry dossier should contain information:
- about the potential registrant
- about the identity of the inquired substance
- where the potential registrant would need to carry out new studies, including those involving vertebrate animals.
LAUS can support you with both, the OR service and the generation of the analytical data for the substance identity.
First step of any new registration under UK REACH is to submit an Article 26 inquiry. There are two more szenarios where you should submit an Article 26 inquiry to HSE:
- You have completed the DUIN and would like to start with the data sharing process.
- DUIN is not possible since you do not fulfill prerequisites.
After the inquiry you will receive your inquiry number and become part of a substance group - a group of potential co-registrants of the same substance (formerly known as SIEF under EU REACH). This will enable you to engage in the data sharing process for a successful registration within the applicable timeframe. Questions? Click here or contact us!
LAUS will be visiting Chemspec in Franfurt on May 31 and June 1. We offer GLP testing for regulatory purposes as e.g. for the registration of your chemicals under REACH, for CLP/GHS and much more.
This will be a good opportunity to meet and to discuss upcoming projects which require testing/experimental endpoints.
If you are interessted, please, contact us for an appointment. We are looking forward to meeting you in Frankfurt!
On May 19, 2022, the “Firmenlauf Südpfalz” finally took place as a live event after two virtual runs.
3,012 participants from 164 companies completed the 5 km course and were happy about their sporting successes or simply about the community experience, which had not been possible for so long. LAUS had 9 participants running. Congratulations to everyone!
The use of NAMs (New Approach Methodology / non-animal alternative methods) is requested for the safety assessment of cosmetic ingredients and cosmetic products wherever possible. For eye/skin and mutagenicity evaluation LAUS offers the following ECVAM validated methods: