News

23.05.2023

We use Human Blood for Genotoxicity Testing acc. to OECD 487

The Micronucleus Assay is an in vitro study to evaluate the mutagenicity/genotoxicity induced by chemical substances:

OECD 487 In Vitro Mammalian Cell Micronucleus Test

detection of micronuclei in the cytoplasm of interphase cells
test system: human lymphocytes freshly obtained by venipuncture

We have increased our capacities and can offer good timelines!

#LAUSgroup #mutagenicity #Moly #Micronucleus

https://www.laus.group/en/performance-profile/mutagenicity-genotoxicity

15.05.2023

We believe that technology and sustainability go hand in hand

Our new LC-MS/MS (Waters Xevo TQ Absolute Triple Quadrupole) guarantees accurate results while reducing environmental impact. The system's reduced energy consumption and use of resources (synthetic air) make it a good choice for labs looking to minimize their carbon footprint. Paired with our highly qualified study directors this makes us a strong partner for your analytical work under GLP.

https://www.laus.group/en/performance-profile/analytical-chemistry

#LAUS.group #analyses #LCMSMS

15.05.2023

Specific testing for Biocidal Spray Products

For Biocidal Spray Products we offer specific analyses in addition to the standard requirements for biocides:

spray pattern
internal pressure of spray cans
discharge rate
clogging

The tests could be integrated into stability studies such as shelf life, accelerated or cold storage.

#LAUSgroup #BPR #spray

17.04.2023

Biodegradability: very good timelines!

At the moment LAUS can offer very good timelines for Biodegradability testing. Based on our extensive experience in this area we have streamlined our processes and increased our capacities. Contact us today!

https://www.laus.group/en/performance-profile/ecotoxicology/biodegradation

#LAUSgroup #Biodegradability #GLP #Biodegradation

13.04.2023

LAUS testing ABC: M for “Moly” and “Micronucleus”

The Mouse Lymphoma Assay acc. to OECD 490 (short “Moly”) and the Micronucleus Assay acc. to OECD 487 are both in vitro studies to evaluate the mutagenicity/genotoxicity induced by chemical substances.

OECD 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene

detection of gene mutations
test system: mouse lymphocytes (L5178Y TK+/- clone (3.7.2C))

OECD 487: In Vitro Mammalian Cell Micronucleus Test

detection of micronuclei in the cytoplasm of interphase cells
test system: human lymphocytes freshly obtained by venipuncture

We have increased our capacities and can offer good timelines!

#LAUSgroup #mutagenicity #Moly #Micronucleus

https://www.laus.group/en/performance-profile/mutagenicity-genotoxicity

04.04.2023

Happy Easter!

OECD 497

We Welcome Our New Team Members

We are more than happy to announce that we were able to fill 7 open positions with highly qualified personnel, both from intern and extern:

study directors in vitro toxicology (2)
study director ecotoxicology
technician analytical chemistry
technicians physico-chemistry (2)
technicians in vitro toxicology (2)
internship/master’s thesis ecotoxicology

They will strengthen our team starting in the first months of 2023. Welcome everyone!

#LAUSgroup #welcome

07.02.2023

Meet us at ChemUK 2023

OECD 497: Defined Approaches (DAs) on Skin Sensitisation

OECD 497 provides Defined Approaches (DAs) for Skin Sensitisation assessment. It allows the Hazard Potential Identification (skin sensitiser / non-sensitiser) and GHS Classification into Potency subcategories 1A and 1B (H317) without animal tests.

Multiple information sources are taken into consideration to come to a conclusion:

In chemico test data (OECD 442C DPRA)

In vitro study data (OECD 442D KeratinoSens, OECD 442E h-CLAT)

In silico predictions (QSAR, DEREK Nexus)

Literature

https://www.laus.group/en/performance-profile/toxicology/in-vitro-toxikologie

#LAUSgroup #OECD497 #invitrosensitisation #animalfree #NAM #skinsensitisation #H317

04.01.2023

Health and Happyness for 2023!

An Automated External Defibrillator(AED) can save lives and it is much easier to use than you would expect. Since this is a matter close to our heart, in the context of the biannual safety check we had a briefing and demonstration of LAUS’ AED. Not only First Aiders could participate, but everyone interested was welcome to see how easy it could be operated. Luckily we yet have not had a situation where we needed it, but this training will hopefully encourage people to act where needed.

We hope you had a good start into the New Year and in this context we wish you Health and Happiness for 2023!

#LAUSgroup #AED #HappyNewYear

20.12.2022

Happy Holidays!

Viscosity of Newtonian and Non-Newtonian fluids

For the determination of the viscosity of liquids acc. to OECD 114 we now have two options:

- falling sphere viscometer (acc. to Höppler) in a range between 0,6 – 70.000 mPa*s and

- rotational viscometer in a range between 3 – 1.000.000 mPa*s

This allows us to test Newtonian as well as Non-Newtonian fluids regarding dynamic viscosity and calculate the kinematic viscosity.

#LAUSgroup #viscosity #newtonianfluid #nonnewtonianfluid #GLP

24.11.2022

New requirements for corrosion to metals testing on biocides

TAB APCP ver 3.0 states that testing on corrosion to metals shall follow the UN Test C.1 AND it must be guaranteed that the content of the active substance throughout the test is kept stable, thus the composition should be checked/analysed throughout the test or at least at the end of the test.

If you are affected, contact us to discuss an individual strategy for testing your biocidal product.

Technical Agreements for Biocides

Analytical Methods, PhysicoChemical Properties and Physical Hazards (APCP)

Version 3.0, September 2022

#LAUSgroup #biocides #metalcorrosion

08.11.2022

Deadline for product authorization of DDAC in PT 1 and PT2

The deadline for applying for product authorization for the active substance DDAC in biocidal products of PT 1 and 2 is 01 February 2024. Good to know that LAUS has already experience with the analytical determination of quaternary ammonium compounds like DDAC. Contact us for more information.

https://www.laus.group/en/product-groups/biocides

#LAUSgroup #BPR #QUATs #DDAC