Hugo Giardini, LAUS Business Development Manager, will be representing our services at the “Nanomaterials and REACh Technical Day” on 7 December 2023 in Paris. Come and talk to him if you have any upcoming nano-related project, we have quite some experience in the area of nanomaterial testing for REACH. Or simply pick up some m&m’s 😊
For Genotoxicity testing of Nanomaterials there are specific requirements detailed in the REACH Appendix R7-1 for nanoforms:
the dispersion of the nanomaterial should be monitored to ensure that the cells are exposed to a sufficient effective dose under in vitro conditions
it is highly advised to verify the cellular uptake by appropriate methods
During the last months we have put a lot of thoughts and research into this topic. We have successfully developed an appropriate approach for our current projects.
As there is a huge diversity in nanomaterials, each test item calls for an individual experimental methodology. So if genotoxicity testing of nanomaterials is something you are concerned with, we would be more than happy to share our experience and discuss a specific strategy for you.
The volunteers at Tafel Edenkoben (food bank) are doing great work supplying many people in need not only with food but also with furniture, clothes and toys. A new refrigerated delivery vehicle has been acquired in order to transport cooled goods. Funding was made possible by advertisements on the autobody. We at LAUS gladly support their work with an advertisement.
To the delight of our staff the latest addition to our technical equipment is a brand-new BBQ (on top of a GC-MS/MS and another LC-MS/MS, of course). Whereas the BBQ is for internal use only (and has been inaugurated already), the GC-MS/MS (Triple Quadrupole) and LC-MS/MS (Triple Quadrupole) are ready to use and waiting for new analytical challenges. If you have any analytical work on difficult substances to do, contact us to discuss our possibilities.
Our new LC-MS/MS (Waters Xevo TQ Absolute Triple Quadrupole) guarantees accurate results while reducing environmental impact. The system's reduced energy consumption and use of resources (synthetic air) make it a good choice for labs looking to minimize their carbon footprint. Paired with our highly qualified study directors this makes us a strong partner for your analytical work under GLP.
At the moment LAUS can offer very good timelines for Biodegradability testing. Based on our extensive experience in this area we have streamlined our processes and increased our capacities. Contact us today!
OECD 497 provides Defined Approaches (DAs) for Skin Sensitisation assessment. It allows the Hazard Potential Identification (skin sensitiser / non-sensitiser) and GHS Classification into Potency subcategories 1A and 1B (H317) without animal tests.
Multiple information sources are taken into consideration to come to a conclusion:
In chemico test data (OECD 442C DPRA)
In vitro study data (OECD 442D KeratinoSens, OECD 442E h-CLAT)