Chemikalien
Korea REACH
Korea REACH
AREC ("Act on the Registration and Evaluation of Chemical Substances") has been in force since January 1, 2015, and the revised version since January 1, 2019. This is also referred to as K-REACH.
New chemicals with a volume of ≥0.1ton/year and existing chemicals ≥1 ton/year must be registered under K-REACH in order to authorize manufacture, import, use and sale. Domestic manufacturers or importers are obliged to register and foreign manufacturer could appoint an Only Representative (OR) to fulfill their legal obligation.
Data requirements
Physico-chemical Properties
Test Method OECD TG |
0.1-1 t/a |
1-10 t/a |
10-100 t/a |
100-1,000 t/a |
>1,000 t/a |
|
Physical state |
|
X |
X |
X |
X |
X |
Water solubility |
105 |
X |
X |
X |
X |
X |
Melting/freezing point |
102 |
X |
X |
X |
X |
X |
Boiling point |
103 |
X |
X |
X |
X |
X |
Vapor pressure |
104 |
X |
X |
X |
X |
X |
Partition coefficient n-octanol/water |
117, 107, 123 |
x |
x |
x |
x |
|
Relative density |
109 |
X |
X |
X |
X |
|
Granulometry |
110 |
X |
X |
X |
X |
|
Flammability |
|
X |
X |
X |
||
Explosive property |
|
X |
X |
X |
||
Oxidizing property |
|
X |
X |
X |
||
Viscosity |
114 |
O |
O |
|||
Dissociation costant |
112 |
O |
O |
Toxicology
Test Method OECD TG |
0.1-1 t/a |
1-10 t/a |
10-100 t/a |
100-1,000 t/a |
>1,000 t/a |
|
Acute oral toxicity*) |
423 |
x |
x |
x |
x |
x |
Acute dermal toxicity (or inhalation) *) |
402, 403 |
x (O) |
x (O) |
x (O) |
||
Skin corrosion/irritation*) |
404 |
x |
x |
x |
x |
|
Eye corrosion/irritation*) |
405 |
x |
x |
x |
||
Skin sensitization*) |
406/429 |
x |
x |
x |
x |
|
Ames test |
471 |
x |
x |
x |
x |
x |
In vitro chromosome aberration |
473/487 |
x |
x |
x |
||
In vitro gene mammalian or |
476, 474/475 |
x |
x |
x |
||
Additional mutation test (germ cell mutagenicity etc.) *) |
O |
O |
||||
Repeated toxicity (28 days) *) |
407/410/412 |
x |
x |
x |
||
Repeated toxicity (90 days) *) |
408/409, 411, 413 |
O |
||||
Carcinogenicity*) |
451/453 |
O |
||||
Screening for reproductive/development toxicity*) |
421/422 |
O |
O |
O |
||
Pre‐natal developmental toxicity study*) |
414 |
O |
||||
Two‐generation reproductive toxicity*) |
416 |
O |
Ecotoxicology
Test Method OECD TG |
0.1-1 t/a |
1-10 t/a |
10-100 t/a |
100-1,000 t/a |
>1,000 t/a |
|
Short-term fish toxicity |
203 |
x |
x |
x |
x |
x |
Short-term daphnid toxicity |
202 |
x |
x |
x |
x |
|
Algae growth inhibition |
201 |
x |
x |
x |
||
Long-term fish toxicity |
210/212/215 |
O |
O |
|||
Long-term daphnid toxicity |
211 |
O |
O |
|||
Short-term toxicity to plants*) |
227 |
O |
O |
|||
Long-term toxicity testing on plants*) |
O |
|||||
Short-term toxicity to invertebrates (earthworm) |
207 |
O |
O |
|||
Long-term toxicity testing on invertebrates (earthworm) |
222 |
O |
||||
Long-term toxicity to sediment organisms |
218/219 |
O |
||||
Activated sludge respiration inhibition test |
209 |
O |
O |
|||
Ready biodegradability |
301/310 |
x |
x |
x |
x |
x |
Hydrolysis as a function of pH |
111 |
x |
x |
x |
||
Inherent biodegradability |
302 |
O |
O |
|||
Identification of degradation products |
O |
O |
||||
Bioconcentration*) |
305 |
O |
||||
Adsorption/desorption screening test |
106/121 |
O |
O |
|||
Additional adsorption/desorption screening |
O |
|||||
Fate and behavior in the environment |
O |
x: GLP study required
X: non-GLP study sufficient
O: can be replaced by test plan
*): subcontracted study
IVT: in vitro alternative available
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